Much to my disappointment I have had to admit defeat, ring up the medical centre and I am now no longer taking part in the Thrive trial of Niacin. The flushing, burning, itching, prickly side effects that are normally encountered as a side effect didn’t occur for me on my face, (well apart from about half an hour following the first nights dose) but on my legs.
This also began following the first dosage. It was at that point just affecting my feet and ankles. Then after each successive dose, it slowly crept upwards in both legs until by the time it came to Friday it was above my knees. It was very uncomfortable because both my legs were also swollen and itchy but the worst part was that it was keeping me awake at night, therefore by the time it came to Friday and I had experienced three nights with hardly any sleep, I had to admit defeat and ring up the Medical Centre who are responsible for this trial.
A lovely doctor spoke to me on the phone (you are provided with a free phone number to ring in case of problems encountered) and after I had told her all my symptoms, she advised not to take any more of the niacin tablets and to contact my GP’ surgery for some more of the ordinary Simvastin 40mg which are normally supplied by them. She also followed up by phoning me on the following day just to check if I was okay and to also run through what to do now regarding my next appointment at Huddersfield hospital with the study nurse and to return the remaining tablets then.
I am bitterly disappointed to have to stop the trial, although the doctor reassured me that my small contribution had been helpful and worthwhile. I suppose that I feel that during my life I haven’t really contributed all that much to others, and this was one way of ‘giving something back’. Silly I know, but that is how I felt about it.
Oh well, I should really have expected this as my skin can react to the fresh air if it feels so inclined!